Activation Of Caspase Activity In Rat Liver Cells By Methanol Extract Of Gloriosa Superba

Activation of caspase 3&9 by methanol extract of Gloriosa superba ABSTRACTMitochondrion is the key regulator in cellular energy homeostasis and plays a central role in determining cell apoptotic process; it is therefore regarded as a vital target for cancer chemotherapy. Cancer is obviously one of the most common areas where demand for alternative treatment is overwhelming. Many investigations revealed that bioactive compounds in natural products can act on mitochondria to trigger the permeabilization of the mitochondrial outer membrane and lead to the impairment of the mitochondria, including…