The Effects Of Cryptolepis Sanguinolenta Root Extracts On Plasmodium Falciparum Gametocyte Development

ABSTRACT Current efforts to eliminate malaria worldwide are soaring and one of the approaches to this is the mass screening of medicinal plants for their possible potential anti-malarial property. The current study conducted was to determine the effect of one such plant, Cryptolepis sanguinolenta on gametocyte development. In vitro growth inhibition assays on early and late gametocytes stage using ethanolic and aqueous extract of the C. sanguinolenta roots was performed. Enzyme activity assays were conducted to determine the effect of C. sanguinolenta ethanolic extract on aconitase, citrate s…