Evaluation Of The Toxicity And Anthelminthic Effect Of Methanol Extract Of Duranta Erecta Fruits

ABSTRACT The chemotherapy of gastrointestinal helminthiasis relies mainly on the use of anthelmintics. However, concerns over drug resistance have encouraged the search for new drug leads. This project report focused on evaluating the toxicity and anthelminthic effect produced in vitro and in vivo by the methanol extract of Duranta erecta fruits. From the study, the plant extract was found to contain several chemical components including flavonoids, tannins, polyuronides, saponins, glycosides and terpenes. Acute toxicity evaluation of the plant extract showed that the extract had an LD50 grea…