Effects Of Oral Administration Of Leaf Extract Of Uvaria Chamae (mmimi Ohia) In Albino Wistar Rats

ABSTRACT Uvaria chamae P. Beauv is known to have various medicinal and therapeutic properties. The Biochemical and toxicological effects of the leaf extract were assessed in this study using Albino wistar rats. Acute toxicity test was performed on the rats to determine the LD50.Sub acute toxicity test was also carried out by oral administration of different doses of ethanolic extract of U. chamae leaf (EEUC) on different groups of rats for thirty (30) days. Twenty (20) male albino wistar rats were divided into four (4) groups A to D (n=5). Animals in group A served as control and received 5%tw…