Effect Of Aqueous Extract Of Cola Nitida On Normal Development Of Distal Gastrointestinal Tract

17 pages ID: MES0117

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DepartmentMedicine And Surgery
TypeProject
Pages17
Reference StyleYES
FormatMS Word & PDF
Reference No.MES0117

Abstract

Background: Normal and abnormal development of anorectum is still under debate. Etiology of abnormal development of anorectum is poorly understood. Caffeine is a vasoconstrictor that has been implicated in abnormal anorectal development and is a major constituent of Kola nut (Cola nitida). It is consumed heavily by pregnant women in Nigeria to control vomiting.  Objectives: We examined the teratogenic effects of oral administration of aqueous extract of Cola nitida (AECON) on foetal growth and development of distal gastrointestinal tract in wistar rats.  Methods: Twelve pregnant Wistar rats us…

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