Anti-ulcerogenic Effects Of Chloroform Extract Of Chasmanthera Dependens On Indomethacin And Aspirin-iduced Ulcer In Rats

Peptic ulcer is one of the leading causes of gastrointestinal surgery with high morbidity and mortality rates. This study assessed the anti-ulcerogenic effect of the chloroform extract of Chasmanthera dependens on indomethacin and aspirin-induced ulcer in rats. Fifty (50) adult rats were divided into two broad groups of twenty five rats each for aspirin and indomethacin models respectively. For each model, twenty five adult rats divided into five groups of four rats each were used for ulcer study. They were acclimatized for one week to laboratory conditions and fed with rat chow and water al l…