Assessment Of Immunogenicity Of Five Infectious Bursal Disease Vaccines Used In Nigeria

ABSTRACT Infectious bursal disease (IBD) causes high morbidity and high mortality among 3 – 6 weeks old chicks. Its occurrence even in vaccinated flocks is a global concern. Passive haemagglutination (PHA) test, a simple and rapid test has been adopted for IBD antibodies but its use for viral titres has not been reported. To modify the test for assessment of viral titres, serial dilutions of a reference IBDV sample were used to sensitize human group O+ red blood cells (RBC) before reacting them with known IBD positive serum. Effect of RBC concentrations (0.1%, 0.2% and 0.6%) on sensitivity of…