Antidiabetic Activities Of The Methanolic Root Bark Extract Of Afzelia Africana In Alloxan-induced Diabetic Mice

ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 250 mg/kg, 500 mg/kg and 1000 mg/kg over a period of 6 hours. The extract was found to have antidiabetic …