CHAPTER ONE 1.0 INTRODUCTION Medicinal plants have been of great important to the health of individual and communities. The medicinal value of these plants had some chemical active substances that produce a definite physiological action on the human body. Nature has served as a rich repository of medicinal plants for thousands of years and an… Continue Reading
TABLE OF CONTENT DECLARATION ............................................................................................................................. i DEDI CA TI 0 N ................................................................................................................................ i i A C K N 0 W LEDG EM ENT… Continue Reading
Background: In Low and Medium income countries (LMICs) focus antenatal care (FANC) services are so low, below the recommended threshold. In Uganda, high maternal and neonatal mortalities have been attributed to the severe variations in F ANC coverage in rural communities. Aim: This study was to determine factors affecting utilization of… Continue Reading
Back ground: Staphylococcus aureus is a gram positive bacteria that exists on the skin as nonnal flora. It is classified as Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin-sensitive Staphylococcus aureus (MSSA), where MRSA is resistant to beta-lactam antibiotics. MRSA has become a predominant pathogen in the health care… Continue Reading
The purpose of this study was to evaluate the antibacterial activity, to determine the most efficiency extractive solvents and phytochemical profile of Hot water, Methanol alcohol and Lemon juice extract of Lawsonia inermis (henna) leaf. The plant attracted the attention of researchers because of its use as anti-infective agent. The oily… Continue Reading
Pharmacovigilance is an essential phenomenon in the rational use of medicine, providing information about ADR in general population. Tracking ADR in' close system pharmacy' which has relied on use of yellow forms and feed back following exposure to drugs has been inadequate. Alternative methods are therefore required. In the present… Continue Reading
Background: Myzus pe.rsicae (green peach aphids) are crop pests; they are among the most destructive insect pests on cultivated plants in temperate regions. Many of them are green in color, but others may be white wooly or black (McGravin,1993).Their damage to plants has made farming a complicated venture across the whole world. From the… Continue Reading
Jackground: Diclofenac is one of the most commonly used non-steroidal anti-inflammatory lrugs (NSAIDs) for the treatment of pain, rheumatism and other inflammatory conditions.Aim: ~his study aimed to investigate whether the selected brands of diclofenac sodium meet heir label specifications as well as the BP 2009.Materials and Methods:… Continue Reading
Pharmaco-economics involves comparing the cost and consequences of products and services and Cost-effectiveness is the relationship between cost and effectiveness of a given drug. ANC of an antacid is one of the ways of evaluating effectiveness of antacid brands. ANC (mEq per unit dose) is the ability of the antacid to neutralize gastric… Continue Reading
This study sought to assess the knowledge on the use of Artemether/ therapy in the management of uncomplicated malaria among out patients treated at KlU-TH. A cross sectional study design was employed in this study. Data was collected from August to October 2018 using a questionnaire by simple Random sampling and was entered and analyzed… Continue Reading
The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense… Continue Reading
Malaria is an enormous public health problem worldwide and kills one to two million people every year, mostly children residing in Africa . And the aim of this study is to determine the impact of combined treatment with Artesunate and Chloroquine on the white blood cell count of plasmodium berghei infected albino mice. And to compare and… Continue Reading
Rauwolfia vomitoria is a natural medicinal herb which has been used over the years for the treatment of hypertension and mental disorders. This is to investigate the inhibitory effect of RAUWOLFIA VOMITORIA aqueous root extract on invitro isolated rabbit intestine precontracted with Acetylcholine. The effect of the root extract was compared with… Continue Reading
ABSTACT The pharmacological effects of the metanolic root extract of the plant Alafia barteri Oliv. used commonly in West and Central Africa, from Guinea Bissau east to Cameroon and south to Congo, including Nigeria for the treatment of various diseases (including malaria, arthritis, eye infection an inflammation) was evaluated. The analgesic… Continue Reading
Peptic ulcer is one of the leading causes of gastrointestinal surgery with high morbidity and mortality rates. This study assessed the anti-ulcerogenic effect of the chloroform extract of Chasmanthera dependens on indomethacin and aspirin-induced ulcer in rats. Fifty (50) adult rats were divided into two broad groups of twenty five rats each for… Continue Reading
Objectives: to explore the anxiolytic activity of ethanolic leaf extract of culcasian scadens in experimental animal models . Methods: The anxiolytic activity was examined by using the elevated plus maze (EPM) and open field test (OFT), hole board test and light and dark box exploration test. Twenty Swiss albino male mice were divided… Continue Reading
TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE---------i DECLARATION--------ii CERTIFICATION--------iii DEDICATION--------iv ACKNOWLEDGEMENT-------v TABLE OF CONTENT-------vi LIST OF TABLES--------ix LIST OF FIGURES-------ix ABSTRACT---------x CHAPTER ONE INTRODUCTION AND LITERATURE REVIEW 1.1 TRADITIONAL MEDICINE-------1 1.2 MODERN MEDICINE--------4… Continue Reading
Landolphia owariensis P. Beauv (Apocynaceae) is a woody liane commonly used in Africa for the treatment of gonorrhea, worm infestation and malaria. The methanol leaf extract (ME) of L. owariensis was obtained by cold maceration and then fractionated into nhexane (nHF), ethylacetate (EF) and methanol (MF) fractions. The methanol extract… Continue Reading
Leaf of Vernonia amygdalina has been shown to have hypoglycemic activity. This may be as a result of the presence of secondary metabolites as its constituents. The major secondary metabolites present in the leaf are tannins, carbohydrates, reducing sugars, glycosides, steroids and proteins. This work was designed to identify these… Continue Reading
Introduction:Tuberculosis (TB) is a communicable disease that has afflicted man for centuries. It is one of the commonest causes of death from infectious diseases in the world. Nigeria is ranked among the 22 countries with the highest TB burden in the world. The discovery of host or pathogen specific biomarkers of TB for diagnosis, treatment, and… Continue Reading
Despite the reported rapid increase in demand for artemisinin and its derivatives, there is little independent collaboration of the toxicity patterns of artemether-lumefantrine combination besides those documented by the manufacturer in its application for approval. It is however, pertinent to conduct an independent evaluation of the… Continue Reading
Cyclophosphamide (CP) is one of the most potent and widely used alkylating anticancer agents. Urotoxicity and myelosuppression is known as the most prevailing dose-limiting toxicity associated with CP. In the present study, the protective potential of Vernonia amygdalina and Ocimum gratissimum aqueous leaf extracts in CP-induced… Continue Reading
Ceiba pentandra is a tropical tree of order Malvales and the family Malvaceae. The basic objective of this research work is to determine the antimicrobial and phytochemical properties of Ceiba pentandra. Fresh leaves and bark of Ceiba petandra was collected at Akungba Akoko. Ceiba pentandra (leaf and bark) were prepared for extraction… Continue Reading
The purpose of this research work is to determine the microbiological profile of hospital solid waste dump sites, sensitivity to antibiotic and isolation and identification of the organism using API 20 E kit method of analysis. Microbiological profiling was carried out on hospital solid waste collected from State Specialist Hospital in… Continue Reading
Anisopus mannii(Asclepiadaceae) –is a glabrous twining shrub, strong climber with greenish flower in globose, lateral umbelliform cymes it is widely used as an anti-diabetic agent in Northern and southern Nigerian traditional medicine, Studies were conducted to determine the phytochemical constituents of leaf and bark ethyl acetate extracts of… Continue Reading